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ACNS00654 Swertia Extract Swertiamarin 98% HPLC

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Swertia Extract Swertiamarin is a naturally occurring secoiridoid glycoside extracted primarily from plants in the Gentianaceae family, such as Swertia Bimaculata, Swertia chirata and Swertia japonica. Widely researched for its diverse bioactive properties, it is utilized in pharmaceuticals, nutraceuticals, and cosmeceuticals. Swertia is a genus in the gentian family. Swertiamarin is used as an active ingredient derived from Swertiapatens (Swertia davida or Swertia bimaculata, Swertia japonica). Swertiamarin is a representative constituent of many crude drugs, which are marketed in Japan and other countries and these crude drugs are normally evaluated by their high swertiamarin content (Takei et al., 2001). It has very low toxicity and is a safe and effective antispastic agent. It showed sedative effect in mice, pigeons and rabbits and induced sleep in mice (Mandal et al., 1998). Its antibacterial, brine shrimp lethality and anticholinergic activities were also reported (Kumarsamy et al., 2003). The study results prove that swertiamarin possess both peripheral and central antinociceptive activity. Swertiamarin are being used to relieve pain. It mainly treats the hepatitis, Oxidation resistance, Antivirus, Increase Immune Function.
This versatile extract is widely utilized in the pharmaceutical field and cosmetics for anti-aging and skin benefits.

1. Production Details:

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Specifications:

ACNS00654 Swertia Extract Swertiamarin 98% HPLC
Botanical Source: Swertia Bimaculata
Assay: HPLC (High-Performance Liquid Chromatography)
CAS No.: 17388-39-5

Molecular formula: C16H22O10

Molecular weight: 374.34
Specifications: Swertiamarin 30%, 50%, and 98% HPLC
Active Compound: Swertiamarin

Testing Method:
High-Performance Liquid Chromatography (HPLC)

ensures purity, typically ranging from a

concentrated 10% extract up to high-purity 98% isolates.
Source: Derived from the herb of

the Swertia Bimaculata plant (often called Du Zhong

in Traditional Chinese Medicine)

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2. Function:

Depression: 5-HTP deficiencies are believed to contribute to depression. 5-HTP supplementation has been shown to be effective in treating mild to moderate depression. In clinical trials 5-hydroxytryptophan showed similar results to those gained with the antidepressant drugs imipramine and fluvoxamine.
Fibromyalgia: Studies show that 5-HTP enhances serotonin synthesis, which increases pain tolerance and sleep quality. Patients with fibromyalgia have reported an improvement in symptoms of depression, anxiety, insomnia, and somatic pain (number of painful areas and morning stiffness).
Insomnia: In many trials, 5-HTP has reduced the time required to fall asleep and improved quality of sleep for those suffering from insomnia.
Migraines: 5-HTP reduced the frequency and severity of migraine headaches in clinical trials. Also, significantly fewer side effects were observed with 5-HTP compared to other migraine headache drugs.
Obesity: 5-hydroxytryptophan creates a fuller feeling - satisfying a person's appetite sooner. Thus allowing patients to stick with diets easier. It has also been shown to decrease the carbohydrate intake in obese patients.
Children's Headaches: Children with sleep disorder-related headaches seem to respond to 5-HTP treatment.